CURRICULUM
VITAE
|
Jin-Wu
Tsai, Ph.D.
Dean of Research and Development
Distinguished Professor, Institute of Brain Science
(IBS), Collegeof Medicine
National
Yang Ming Chiao Tung University (NYCU)
155 Li-Nong St. Sec. 2, Beitou 112, Hsinchu/Taipei,
Taiwan
Tel: +886-2-2826-7305
Fax: +886-2-2827-3123
E-mail: tsaijw@ym.edu.tw
http://bml.ym.edu.tw/ibs/brain/TsaiLab/
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APPOINTMENTS:
- 2021-Present:
Dean of Research and Development, NYCU, Hsinchu,
Taiwan
- 2021-Present:
Distinguished Professor, IBS, Collegeof Medicine,
NYCU, Taipei, Taiwan
- 2021-Present:
Adjunct Professor, Department of Biological Science
& Technology, NYCU, Hsinchu, Taiwan
- 2020-2021:
Professor, IBS, School of Medicine, National Yang-Ming University
(NYMU), Taipei, Taiwan
- 2020-2021:
Deputy Director of Research and Development, NYMU, Taipei,
Taiwan
- 2020-2021:
Chief of General Planning Section, Office of Research and
Development, NYMU, Taipei, Taiwan
- 2019-2021:
Adjunct Associate Professor, Department of Biological Science
& Technology, National Chiao Tung University (NCTU),
Hsinchu, Taiwan
- 2018-2020:
Associate Professor, IBS, School of Medicine, NYMU, Taipei,
Taiwan
- 2012-2018:
Assistant Professor, IBS, School of Medicine, NYMU, Taipei,
Taiwan
- 2010-2012:
Scientific Manager, Department of Biomedical Imaging, Early
Research and Development, Genentech Inc.
- 2009-2010:
Postdoctoral Scholar, Eli and Edythe Broad Center of Regeneration
Medicine and Stem Cell Research, University of California,
San Francisco (UCSF)
- 2008-2009:
Postdoctoral Fellow, Skirball Institute of Biomolecular
Medicine, New York University (NYU) Langone Medical Center,
New York
EDUCATION:
-
2002-2008: Ph.D., Integrated Program in Cellular, Molecular,
and Biophysical Studies, Columbia
University, New York, USA
- 1998-2000:
M.S., Microbiology
and Immunology, National
Yang-Ming University (NYMU), Taipei, Taiwan
- 1994-1998:
B.S., double degree in Physics
and in Zoology,
National
Taiwan University (NTU), Taipei, Taiwan
RESEARCH
INTERESTS AND SPECIALTIES:
- Physics:
General optics, Laser optics, Two-photon microscopy, Confocal
microscopy, Fluorescence lifetime imaging microscopy (FLIM),
Light microscopy
- Biology:
Neural development, Stem cell biology, Neural degenerative
diseases, Alzheimer's disease, In utero electroporation,
Stroke, Tramatic brain injury, Cell and brain slice culture,
Live cell imaging
- Computer:
Digital image process and analysis, Computer programming
(MatLab), Web design
HONORS:
- 2021:
The 2nd Kenneth K. Wu Lecture
- 2021:
The 17th VGH-UST Outstanding Research Articles-Runner-up
- 2020:
Outstanding Research Award, Ministry of Science and
Technology, Taiwan
- 2020:
Eiplepsy Research Award, Taiwan Epilepsy Society
- 2015-2020:
Medical Student-Elected Excellent Teaching Award,
NYMU School of Medicine
- 2019:
TienTe Lee Award for Medical and Pharmacological Technologies
(Young Investigators)
- 2019:
Excellent Teaching Award, National Yang-Ming University
- 2019:
Academia Sinica Research Award for Junior Research Investigators,
Academia Sinica
- 2019:
The 17th Y. Z. Hsu Science Paper Award, Far Eastern
Y. Z. Hsu Science and Technology Memorial Foundation
- 2019:
Epilepsy Research Articles of the Year, First Place,
Taiwan Epilepsy Society
- 2018,
2015: Excellent Teaching Award, National Yang-Ming
University
- 2018
Runner-up in the VGH-UST Research Grant Poster Contest
- 2017,
2014: Outstanding Young Investigator Research Grant,
Ministry of Science and Technology
- 2014-2015
The 8th "France-Taiwan Frontiers of Science"
Planning Group Member, Ministry of Science and Technology
- 2011:
Recognition Award, Genentech Inc.
- 2011:
Ruth L. Kirschstein National Research Service Awards
for Individual Postdoctoral Fellows, National Institutes
of Health, USA
- 2010:"Study
Abroad" Postdoctoral Fellowship, National Science
Council, Taiwan
- 2008:
Spinal Cord Injury Research Program Postdoctoral Fellowship
Award, Spinal Cord Injury Research Board (SCIRB), New
York State Department of Health
- 2008:
The Rover Award for Outstanding Achievement in Anatomy
and Cell Biology
- 2008:
Ph.D. degree with Distinction, Columbia University
- 2007:
International Brain Research Organization Travel Grant
for the World Congress of Neuroscience
- 2007:
The British Council Stem Cell Workshop Scholarship
- 2006:
AAAS/Science Program for Excellence in Science
- 2006:
NIH National Graduate Student Research Festival Scholarship
- 2006:
Taiwanese Bioscientist Association Student Travel Award
- 2005:
The Brunie Prize in Neural Stem Cell Research
- 2005:
American Society for Cell Biology (ASCB) Predoctoral
Student Travel Award
- 2000:
The Best Student Paper Award, International Society
for Optical Engineering
- 2000:
Outstanding Thesis Award, National Yang-Ming University
- 1998:
Wu Chien-Shiung Science Award, Wu Chien-Shiung Education
Foundation
- 1996,
1994: Presidential Award, National Taiwan University
- 1994:
The 25th International Physics Olympiad contestant
- 1994:
The 6th Asian Pacific Mathematics Olympiad contestant
INVITED
PRESENTATIONS:
- Invited
speaker in EMBO Workshop on Neural Development and Neurodegeneration,
Taipei, Taiwan (2022)
- Invited
symposium speaker in the 16th Meeting of the Asian-Pacific
Society for Neurochemistry (APSN), Singapore (2021)
- Invited
speaker in the 14th Asia Pacific Federation of Pharmacologist
(APFP), Taipei, Taiwan (2021)
- Invited
speaker in the International Conference of Developmental
Biology, Stem Cells and Regenerative Medicine, Taipei, Taiwan
(2021)
- Invited
speaker and panelist in the International Brain Research
Organization (IBRO) Associate School on Neuromics, Kuala
Lummpur, Malaysia (2021)
- Invited
speaker in the 34th International Epilepsy Congress, Paris,
France (2021)
- Invited
speaker in the 5th NHRI-ToMMo Conference, Tohoku, Japan
(2019)
- Invited
speaker in AsiaPacific Forum on Population Genomics, Taipei,
Taiwan (2019)
- Invited
speaker in the Taiwan Society for Biochemistry and Molecular
Biology Autumn Camp (2018)
- Invited
speaker in the 23rd Congress of Chinese Pediatric Society,
Xiamen, China (2018)
- Invited
speaker in the 12th NYMU-UCSD Bilateral Symposium, La Jolla,
CA (2018)
- Invited
speaker in the Annual Meeting of the Association for the
Study of Neurons and Diseases, Taipei, Taiwan (2018)
- Invited
speaker in the Cross-Strait Epilepsy Gene Research Forum,
Taipei, Taiwan (2018)
- Invite
speaker in the 3rd Cross-Strait Epilepsy Junior Summit,
Changchun, China (2018)
- Keynote
speaker in the Asia Pacific Medical Student Symposium (APMSS),
Taipei, Taiwan (2017)
- Invited
speaker in the 10th NYMU-UCSD Bilateral Symposium, La Jolla,
CA (2016)
- Invited
symposium speaker in the 14th Meeting of the Asian-Pacific
Society for Neurochemistry (APSN), Kuala Lumpur, Malaysia
(2016)
- Invited
speaker in Focus on Microscopy 2016 conference , Taipei,
Taiwan (2016)
Invited symposium speaker in the 6th Federation of Asia-Oceanian
Neuroscience Society (FAONS) Congress and the 11th Biennial
Conference of CNS, Wuzhen, China (2015)
- Invited
speaker in the 25th ISN-APSN-ASN Joint Meeting Satellite
Meeting, Cairns, Australia (2015)
- Invited
speaker in the 4th Symposium of World Association of Chinese
Epileptologists (WACE), Kaohsiung, Taiwan (2014)
- Invited
speaker in the 4th Annual World Congress of Molecular &
Cell Biology Meeting, Dalian, China (2014)
- Invited
speaker in the 12th Annual Meeting of the Taiwan Epilepsy
Society, Taipei, Taiwan (2014)
- 2013:
Invited speaker in the Conference of the Federation of Asian
Societies for Molecular Imaging, Taipei, Taiwan
- 2013:
Invited speaker in the Combined ASBMB, ASPS, and ANZSCDB
Annual Meeting (ComBio), Perth, Australia
- 2013:
Invited speaker in the International Symposium on Development,
Morphogenesis, and Stem Cells, Taipei, Taiwan
- 2012:
Invited speaker in the 6th NYMU-UCSD Bilateral Symposium,
La Jolla, CA
- 2011:
Invited speaker in the Annual Meeting of Taiwan Neuroscience
Society, Taipei, Taiwan
2010: Invited speaker in the 4th NYMU-UCSD Bilateral Symposium,
La Jolla, CA
- 2009:
Speaker in the 39th Neuroscience Meeting, Chicago, IL, Society
for Neuroscience
- 2009:
Invited speaker in the 2nd Global COE Retreat, Hokuto, Japan,
University of Tokyo
- 2008:
Invited speaker in the 1st Tohoku Neuroscience GCOE conference
"From Genes to Development and Behavior", Zao,
Japan, Tohoku University
- 2007:
Speaker in the "Stem cells, axon guidance and migration
in the developing and adult brain" conference, Cairns,
Australia, IBRO
- 2006:
Invited speaker in the 46th Cell Biology Meeting, San Diego,
CA, ASCB
- 2006:
Invited speaker in the CAS Symposium on Model Organisms
and Diseases, Beijing, China, Chinese Academy of Sciences
- 2006:
Speaker in the 36th Neuroscience Meeting, Atlanta, GA, Society
for Neuroscience
- 2005:
Speaker in the 35th Neuroscience Meeting, Washington, DC,
Society for Neuroscience
- 2004:
Invited speaker in the 44th Cell Biology Meeting, Washington,
DC, ASCB
- 2000:
Invited speaker in Photonics Taiwan 2000, Taipei, Taiwan,
Int'l Society of Optical Engineering
PATENTS:
- Chi-Hung
Lin, Jin-Wu Tsai and Yong-Shyang Yi. "Cell Observing
Method and the System Thereof" Patent
of the Republic of China #00594011 (2004-2020)
PUBLICATIONS:
2021
- Savino
E, Guarnieri FC, Tsai JW, Corradi A, Benfenati F,
Valtorta F* (2021) An
emerging role of PRRT2 in regulating growth cone morphology,
Cells, 10(10):2666.
- Chen
HY, Hsu CL, Lin3 HY, Lin YF, Tsai SF, Ho YJ, Li YR,
Tsai JW, Teng SC*, Lin CH* (2021) Clinical
and functional characterization of a novel STUB1 frameshift
mutation in autosomal dominant spinocerebellar ataxia
type 48 (SCA48). J Biomed Sci, 28(1):65.
2020
- Tsai
MH, Muir AM, Wang WJ, Kang YN, Yang KC, Chao NH, Wu
MF, Chang YC, Porter BE, Jansen LA, Sebire G, Deconinck
N, Fan WL, Su SC, Chung WH, Almanza Fuerte EP, Mehaffey
MG, University of Washington Center for Mendelian
Genomics, Ng CC, Chan CK, Lim KS, Leventer RJ, Lockhart
PJ, Riney K, Damiano JA, Hildebrand MS, Mirzaa GM,
Dobyns WB, Berkovic SF, Scheffer IE, Tsai JW*, Mefford
HC* (2020) Pathogenic
variants in CEP85L cause sporadic and familial posterior
predominant lissencephaly. Neuron,
106(2):237-245. (* corresponding)
- Tsai
MH, Cheng HY, Nian FS, Liu C, Chao NH, Chiang KL,
Chen SF, Tsai JW* (2020) Impairment
in Dynein-Mediated Nuclear Translocation by BICD2
C-terminal Truncation Leads to Neuronal Migration
Defect and Human Brain Malformation. Acta
Neuropathol Commun, 8(1):106. (* corresponding)
- Ibrahim
RB, Yeh SY, Lin KP, Ricardo F, Yu TY, Chan CC, Tsai
JW*, Liu YT* (2020) Cellular
secretion and cytotoxicity of transthyretin mutant
proteins underlie late onset amyloidosis and neurodegeneration.
Cell Mol Life Sci,
77(7):1421-1434. (* corresponding)
- Yang
CP, Yang WS, Wong YH, Wang KH, Teng YC, Chang MH,
Liao KH, Nian FS, Chao CC, Tsai JW, Hwang WL, Lin
MW, Tzeng TY, Wang PN, Campbell M, Chen LK, Tsai TF,
Chang PC, Kung HJ (2020) Muscle
atrophy-related myotube-derived exosomal microRNA
in neuronal dysfunction: Targeting both coding and
long noncoding RNAs. Aging Cell,
19(5):e13107.
- Chang
CY, Liang MZ, Wu CC, Huang PY, Chen HI, Yet SF, Tsai
JW, Kao CF, Chen L (2020) WNT3A
promotes neuronal regeneration upon traumatic brain
injury. Int J Mol Sci, 21(4):1463.
- Hu
CJ, Lu YC, Tsai YH, Cheng HY, Takeda H, Huang CY,
Xiao R, Hsu CJ, Tsai JW, Vandenberghe LH, Wu CC, Cheng
YF (2020) Efficient
in utero gene transfer to the mammalian inner ears
by a synthetic adeno-associated viral vector Anc80L65.
Mol Ther-Methods & Clin Dev, 18:493-500.
(Cover)
2019
- Chang
CH, Zanini M, Shirvani H, Cheng JS, Yu H, Feng CH,
Mercier AL, Hung SY, Forget A, Wang CH, Cigna SM,
Lu IL, Chen WY, Leboucher S, Wang WJ, Ruat M, Spassky
N, Tsai JW*, Ayrault O* (2019) Atoh1
requires primary cilia for the expansion of granule
neuron progenitors by modulating centriolar satellites.
Dev Cell, 48(2):184-199.e5. (* corresponding)
-
Tsai MH, Nian FS, Hsu MH, Liu WS, Liu YT, Liu C, Lin
PH, Hwang DY, Chuang YC, Tsai JW* (2019) PRRT2
missense mutations cluster near C-terminus and frequently
lead to protein mislocalization. Epilepsia,
60(5):807-817. (* corresponding)
- Chen
JL, Chang CH, Tsai JW* (2019) Gli2
rescues delays in brain development induced by Kif3a
dysfunction. Cereb Cortex, 29(2):751-64.
(* corresponding)
- Nian
FS, Li LL, Cheng CY, Wu PC, Lin YT, Tang CY, Ren BS,
Tai CY, Fann MJ, Kao LS, Hong CJ, Tsai JW* (2019)
Rab18
collaborates with Rab7 to modulate lysosomal and autophagy
activities in the nervous system: An overlapping mechanism
for Warburg micro syndrome and Charcot-Marie-Tooth
neuropathy type 2B. Mol Neurobiol,
56(9):6095-6105. (* corresponding)
- Chang
HY, Cheng HY, Tsao AN, Liu C, Tsai JW* (2019) Multiple
functions of KBP in neural development underlie brain
anomalies in Goldberg-Shprintzen syndrome. Front
Mol Neurosci, 12:265. (* corresponding)
- Ibrahim
RB, Liu YT, Yeh SY, Tsai JW* (2019) Contributions
of animal models to the mechanisms and therapies of
transthyretin amyloidosis. Front Physiol,
10:338. (* corresponding)
- Valente
P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte
N, Fruscione F, Castroflorio E, Michetti C, Giansante
G, Valtorta F, Tsai JW, Zara F, Nieus T, Corradi A,
Fassio A, Baldelli P, Benfenati F (2019) Constitutive
inactivation of the PRRT2 gene alters short-term synaptic
plasticity and promotes network hyperexcitability
in hippocampal neurons. Cereb Cortex,
29(5):2010-2033.
2018
- Lu
IL, Chen C, Tung CY, Chen HH, Pan JP, Chang CH, Cheng
JS, Chen YA, Wang CH, Huang CW, Kang YN, Chang HY,
Li LL, Chang KP, Shih YH, Lin CH, Kwan SY, Tsai
JW* (2018) Identification
of genes associated with cortical malformation using
a transposon-mediated somatic mutagenesis screen in
mice. Nat Commun, 9(1):2498. (*
corresponding)
- Hsiao
CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ,
and Tsai JW* (2018) Gli2
modulates cell cycle re-entry through autophagy-mediated
regulation on the length of primary cilia. J
Cell Sci, 131(24). pii: jcs221218. (* corresponding)
- Chen
YA, Lu IL, Tsai JW* (2018) Contactin-1/F3
regulates neuronal migration and morphogenesis through
modulating RhoA activity. Front Mol Neurosci,
11:422. (* corresponding)
- Jheng
GW, Hur SS, Chang CM, Wu CC, Cheng JS, Lee HH, Chung
BC, Wang YK, Lin KH, del Alamo JC, Chien S, Tsai
JW* (2018). Lis1
dysfunction leads to traction force reduction and
cytoskeletal disorganization during cell migration.
Biochem Biophys Res Commun, 497, 869-75.
(* corresponding)
- Kilander
MBC, Wang CH, Chang CH, Nestor JE, Herold K, Tsai
JW, Nestor MW, Lin YC (2018) A
rare human CEP290 variant disrupts the molecular integrity
of the
primary cilium and impairs Sonic Hedgehog machinery.
Sci Rep, 8(1):17335.
2017
- Chen
HR, Juan HC, Wong YH, Tsai JW, Fann MJ (2017)
Cdk12
regulates neurogenesis and late-arising neuronal migration
in the developing cerebral cortex. Cereb
Cortex, 27:2289-302.
- Chakraborty
S, Karmenyan A, Tsai JW, Chiou A (2017) Inhibitory
effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium
(MPP+) induced neurotoxicity in differentiated PC12
cells. Sci Rep, 7, 16977.
- Liu
YH, Tsai JW, Chen JL, Yang WS, Chang PC, Cheng
PL, Turner DL, Yanagawa Y, Wang TW, Yu JY (2017) Ascl1
promotes tangential migration and confines migratory
routes by induction of Ephb2 in the telencephalon.
Sci Rep, 7, 42895.
2016
-
Liu YT, Nian FS, Chou WJ, Tai CY, Kwan SY, Chen C,
Kuo PW, Lin PH, Chen CY, Huang CW, Lee YC, Soong BW*,
Tsai JW* (2016) PRRT2
mutations lead to neuronal dysfunction and neurodevelopmental
defects. Oncotarget, 7, 39184-96.
(* corresponding)
-
Tsai MH, Kuo PW, Myers CT, Li SW, Lin WJ, Fu TY, Chang
HY, Mefford HC, Chang YC*, Tsai JW* (2016).
A
novel DCX missense mutation in a family with X-linked
lissencephaly and subcortical band heterotopia syndrome
inherited from a low-level somatic mosaic mother:
Genetic and functional studies. Eur J Paediatr
Neurol, 20, 788-94. (* corresponding)
- Chakraborty
S, Nian FS, Tsai JW, Karmenyan A, Chiou A (2016)
Quantification
of the metabolic state in cell-model of Parkinson's
disease by fluorescence lifetime imaging microscopy.
Sci Rep, 6, 19145.
- Ma
L*, Qiao Q*, Tsai JW*, Yang G, Li W, Gan WB
(2016) Experience-dependent
plasticity of dendritic spines of layer 2/3 pyramidal
neurons in the mouse cortex. Dev Neurobiol,
76, 277-286. (*equal contribution)
- Qiao
Q, Ma L, Li W, Tsai JW, Yang G, Gan WB (2016)
Long-term
stability of axonal boutons in the mouse barrel cortex.
Dev Neurobiol, 76, 252-261.
2015
-
Cheng CY, Wu JC, Tsai JW, Nian FS, Wu PC, Kao
LS, Fann MJ, Tsai SJ, Liou YJ, Tai CY, Hong CJ (2015)
ENU
mutagenesis identifies mice modeling Warburg Micro
syndrome with sensory axon degeneration caused by
a deletion in Rab18. Exp Neurol,
267, 143-151.
2011
- Tsai
JW & Vallee RB (2011) Live
microscopy of neural stem cell migration in brain
slices. Methods Mol Biol, 750:131-42.
- Wang
X, Tsai JW, Lamonica B & Kriegstein AR
(2011) A
new subtype of progenitor cell in the mouse embryonic
neocortex. Nat Neurosci, 14, 555-561.
(Cover; featured in News and Views)
2010
- Tsai
JW*, Lian WN*, Kemal SK, Kriegstein AR & Vallee
RB (2010) Kinesin
3 and cytoplasmic dynein mediate interkinetic nuclear
migration in neural stem cells. Nat Neurosci,
13, 1463-1471. (*equal contribution)
2009
- Wang
X, Tsai JW, Imai JH, Lian WN, Vallee RB &
Shi SH (2009) Asymmetric
inheritance of centrosome maintains neural progenitors
during mammalian neocortical neurogenesis. Nature
461, 947-955. (Cover; featured in News and Views)
- Vallee
RB, Seale GE & Tsai JW (2009) Emerging
roles for myosin II and cytoplasmic dynein in migrating
neurons and growth cones. Trends Cell Biol
19, 347-355.
2007
- Tsai
JW , Bremner KH & Vallee RB. Dual
subcellular roles for LIS1 and dynein in radial neuronal
migration in live brain tissue. Nat Neurosci
10, 970-979 (2007).
2006
- Richard
B. Vallee and Jin-Wu Tsai. The
Cellular Roles of the Lissencephaly Gene LIS1, and
What They Tell Us About Brain Development. Genes
& Development 20, 1384-1393 (2006). (Perspective)
- Chia-Fen
Hsieh, Bo-Jui Chang, Chyi-Huey Pai, Hsuan-Yi Chen,
Jin-Wu Tsai, Yung-Hsiang Yi, Yi-Ting Chiang,
Da-Wei Wang, Sien Chi, Long Hsu, and Chi-Hung Lin.
Stepped
changes of monovalent ligand-binding force during
ligand-induced clustering of integrin aIIbb3.
The Journal of Biological Chemistry
281, 25466-25474 (2006).
2005
- Jin-Wu
Tsai, Yu Chen, Arnold R. Kriegstein, and Richard
B. Vallee. LIS1
RNAi blocks neural Stem cell division, morphogenesis,
and motility at multiple stages. The Journal
of Cell Biology 170, 935-945 (2005). (Journal
cover and highlight paper)
2004
- Chia-Fen
Hsieh, Bo-Jui Chang, Chyi-Huey Pai, Hsuan-Yi Chen,
Sien Chi, Long Hsu, Jin-Wu Tsai, and Chi-Hung
Lin. Identification of stepped changes of binding
affinity during interactions between the disintegrin
rhodostomin and integrin aIIbbIII in living cells
using optical tweezers. Proceedings of SPIE
5514, 215-224 (2004).
2001
-
Jen-Chang Liu, Wen-Liang Hwang, Ming-Syan Chen, Jin-Wu
Tsai, and Chi-Hung Lin. Wavelet-based Active Contour
Model for Object Tracking. ICIP Proceedings
3, 206-209 (2001).
2000
-
Chi-Hung
Lin and Jin-Wu Tsai. [Applications
of optical tweezers in biological force measurements.]
Physics Bimonthly 22, 500-505 (2000).
(Chinese)
- Jin-Wu
Tsai, Bing-Yao Liao, Chun-Cheng Huang, Wen-Liang
Hwang, Da-Wei Wang, Arthur E. Chiou, and Chi-Hung
Lin. Applications of optical tweezers and an integrated
force measurement module for biomedical research.
Proceedings of SPIE 4082, 213-221 (2000).
(Best Student Paper Award)
1999
- Wei-Nan
Lian, Jin-Wu Tsai, Pang-Mien Yu, Tzu-Wei Wu,
Shun-Chun Yang, Yat-Pang Chau, and Chi-Hung Lin. Targeting
of aminopeptidase N to bile canaliculi correlates
with secretory activities of the developing canalicular
domain. Hepatology 30, 748-760 (1999).
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CONFERENCE
ABSTRACTS:
- Tsai
JW, Hedehus M, Kallop D, Weimer R. An interactive semi-automatic
dendritic spine detection tool for efficient quantification
of synaptic dynamics in vivo. Imaging in 2020 VII, Jackson
Hole, WY (2011)
- Wang
X, Tsai JW, Lamonica B, Kriegstein AR. The cellular
roles for MCPH genes CDK5RAP2 and CPAP in cortical development.
ISSCR 8th Annual Meeting, San Francisco, CA (2010)
- Lian
WN, Tsai JW & Vallee RB. Cytoplasmic dynein and
nonconventional kinesin responsible for bidirectional interkinetic
nuclear oscillations in neuroepithelial cells. The 39th
Neuroscience Meeting, Chicago, IL (2009)
- Tsai
JW. From neurogenesis to synaptical genesis: a long
journey for cortical neurons. The 2nd Global COE Retreat,
Hokuto, Japan (2009)
- Tsai
JW, Lian WN & Vallee RB. The molecular basis for
interkinetic nuclear oscillations in the mammalian neuroepithelium.
The 48th Cell Biology Meeting, San Francisco, CA (2008)
- Tsai
JW, Bremner KH & Vallee RB. Subcellular roles for
LIS1 and dynein in radial migration of neurons during embryonic
cortical development. The 1st Tohoku Neuroscience Global-COE
Conference, Zao, Japan (2008)
- Tsai
JW, Bremner KH & Vallee RB. Dynein and LIS1 Transport
the entire microtubule cytoskeleton through in migrating
neural precursors, and myosin IIb brings up the rear. The
47th Cell Biology Meeting, Washington, DC (2007)
- Tsai
JW & Vallee RB. Dual subcellular roles for lis1
and dynein in radial migration of neurons during embryonic
cortical development. IBRO World Congress of Neuroscience,
Melbourne, Australia (2007)
- Jin-Wu
Tsai, Richard B. Vallee. Triple labeling of migrating
neural progenitor cells in live brain tissue reveals novel
roles for cytoplasmic dynein and LIS1 in centrosomal, nuclear,
and microtubule behavior. The 46th Cell Biology Meeting,
San Diego, CA (2006)
-
Jin-Wu Tsai, Richard B. Vallee. Direct observation
of microtubule dynamics in live brain tissue. The 46th Cell
Biology Meeting, San Diego, CA (2006)
- Jin-Wu
Tsai, Richard B. Vallee. Triple labeling of neural progenitor
cells in live brain tissue reveals novel roles for cytoplasmic
dynein and LIS1 in centrosomal and nuclear behavior. The
36th Neuroscience Meeting, Atlanta, GA (2006)
- Jin-Wu
Tsai, Yu Chen, Arnold R. Kriegstein, and Richard B.
Vallee. Multiple effects of LIS1 RNAi on neural progenitor
cell division, polarization, axonogenesis, and motility.
The 45th Cell Biology Meeting, San Francisco (2005).
- Serena
C. Tan, Jin-Wu Tsai, Garrett Seale, and Richard B.
Vallee. Dynein light intermediate chains: A comparison of
distribution and function in fibroblasts and developing
neurons. The 45th Cell Biology Meeting, San Francisco, CA
(2005).
- Jin-Wu
Tsai, Yu Chen, Peter Canoll, Arnold R. Kriegstein, and
Richard B. Vallee. LIS1 RNAi blocks neural progenitor cells
at multiple stages in the radial migration pathway. The
35th Neuroscience Meeting, Washington, DC (2005).
- Richard
B. Vallee and Jin-Wu Tsai. Role of cytoplasmic dynein
and LIS1 in neural progenitor cell migration and division.
International Dynein Workshop, Kobe, Japan (2005).
- Richard
B. Vallee and Jin-Wu Tsai. Role of cytoplasmic dynein
in brain developmental and neurodegerative disease. Experimental
Biology Conference, San Diego, CA (2005).
-
Jin-Wu Tsai, Yu Chen, Richard B. Vallee, and Arnold
R. Kriegstein. Interference with LIS1 and dynactin arrests
neuronal migration at the multipolar stage and interferes
with neocortial expansion. Mol. Biol. Cell 15, 173a
(2004).
- Yong-Shyang
Yi, Jin-Wu Tsai, Chi-Hung Lin, and Szecheng J. Lo.
Platelet and CHO cell adhesion and morphological change
on various recombinant substrates. Mol. Biol. Cell
10, 62a (1999).
- CS
Yang, WN Lian, YJ Chen, TW Wu, PM Yu, JW Tsai, and
CH Lin. Delivery of aminopeptidase N to bile canaliculi
correlates with specific transcytosis activities in human
hepatoma cell lines. Mol. Biol. Cell 9, 91a (1998).
PROFESSIONAL
SOCIETIES:
Updated 02/07/2014. Copyright© 2014
Jin-Wu Tsai. All rights reserved.
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